Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor used in the therapy of many myeloma. Its synthesis or examine is critical for ensuring the purity and protection in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-1): A essential compound inside the synthesis of imatinib, a drug that targets specific different types of cancer, including Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the creation course of action and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilised to treat breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the treatment of breast cancer. A variety of intermediates assist in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers for instance ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal cancer and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have various programs, which include 17b)-7-(9-Bromononyl)-estra-1 antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for style two diabetes that inhibits the enzyme DPP-four to manage blood sugar amounts.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is associated with the synthesis of varied gluconic acid derivatives, which can be Utilized in foods, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A CAS NO. 314771-76-1 precursor from the synthesis of canagliflozin, a medication applied to control form 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).